ARG44832

anti-GBP6 antibody

anti-GBP6 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody recognizes GBP6
Tested Reactivity Hu
Tested Application IHC-P, IP, WB
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Target Name GBP6
Antigen Species Human
Epitope RLGTLAVTYV EAINSGAVPC LENAVITLAQ RENSAAVQRA ADYYSQQMAQ RVKLPTDTLQ ELLDMHAACE REAIAIFMEH SFKDENQEFQ KKFMETTMNK KGDFLLQNEE SSVQYCQAKL NELSKGLMES ISAGSFSVPG GHKLYMETKE RIEQDYWQVP RKGVKAKEVF QRFLESQMVI EESILQSDKA LTDREKAVAV DRAKKEAAEK EQELLKQKLQ EQQQQMEAQD KSRKENIAQL KEKLQMEREH LLREQIMMLE HTQKVQNDWL HEGFKKKYEE
Conjugation Un-conjugated
Alternate Names GBP6; Guanylate Binding Protein Family Member 6; Guanine Nucleotide-Binding Protein 6; Guanylate-Binding Protein 6; GTP-Binding Protein 6; DKFZp686G0786; GBP-6; Guanylate Binding Protein Family, Member 6; EC 3.6.5.-

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100
IP1:100
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A purification
Buffer PBS with 0.09% sodium azide
Preservative 0.09% sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol GBP6
Gene Full Name Guanylate Binding Protein Family Member 6
Background Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).[supplied by OMIM, Dec 2008]
Function Confers protection to several pathogens, including the bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii. [UniProt]
Cellular Localization Cytoplasmic vesicle. [UniProt]
PTM Ubl conjugation. [UniProt]