ARG55461

anti-GDF15 antibody

anti-GDF15 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse

Cell Biology and Cellular Response antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes GDF15
Tested Reactivity Hu, Ms
Predict Reactivity Rat
Tested Application ICC/IF, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GDF15
Antigen Species Human
Immunogen Recombinant protein of Human GDF15 (NP_004855.2)
Conjugation Un-conjugated
Alternate Names Growth/differentiation factor 15; GDF-15; Placental TGF-beta; NAG-1; Macrophage inhibitory cytokine 1; MIC1; NSAID-activated gene 1 protein; PTGFB; NRG-1; MIC-1; PLAB; NSAID-regulated gene 1 protein; PDF; Prostate differentiation factor; Placental bone morphogenetic protein

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:100
IP1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control SW620
Observed Size ~ 36 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 23886 Mouse GDF15

GeneID: 9518 Human GDF15

Swiss-port # Q99988 Human Growth/differentiation factor 15

Swiss-port # Q9Z0J7 Mouse Growth/differentiation factor 15

Gene Symbol GDF15
Gene Full Name growth differentiation factor 15
Background The protein encoded by this gene belongs to the transforming growth factor-beta (TGF-beta) family. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress reponse program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Sep 2015]
Research Area Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Calculated MW 34 kDa