ARG58852
anti-GDNF Receptor alpha 3 antibody
anti-GDNF Receptor alpha 3 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GDNF Receptor alpha 3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GDNF Receptor alpha 3 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 32-240 of Human GDNF Receptor alpha 3 (NP_001487.2). |
| Conjugation | Un-conjugated |
| Alternate Names | GDNFR-alpha-3; GFR-alpha-3; GDNF family receptor alpha-3; GDNFR3; GDNF receptor alpha-3 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | BxPC3 | ||||
| Observed Size | 45 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GFRA3 |
| Gene Full Name | GDNF family receptor alpha 3 |
| Background | The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. [provided by RefSeq, Jul 2008] |
| Function | Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase. [UniProt] |
| Cellular Localization | Cell membrane, Lipid-anchor, GPI-anchor. [UniProt] |
| Calculated MW | 45 kDa |
| PTM | N-glycosylated. [UniProt] |
