ARG59987
anti-GINS2 / PSF2 antibody
anti-GINS2 / PSF2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GINS2 / PSF2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GINS2 / PSF2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-185 of Human GINS2 (NP_057179.1). |
| Conjugation | Un-conjugated |
| Alternate Names | HSPC037; PSF2; DNA replication complex GINS protein PSF2; Pfs2; GINS complex subunit 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Jurkat | ||||
| Observed Size | 21 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9Y248 Human DNA replication complex GINS protein PSF2 |
|---|---|
| Gene Symbol | GINS2 |
| Gene Full Name | GINS complex subunit 2 (Psf2 homolog) |
| Background | The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008] |
| Function | The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 21 kDa |
