ARG59987

anti-GINS2 / PSF2 antibody

anti-GINS2 / PSF2 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes GINS2 / PSF2
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GINS2 / PSF2
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-185 of Human GINS2 (NP_057179.1).
Conjugation Un-conjugated
Alternate Names HSPC037; PSF2; DNA replication complex GINS protein PSF2; Pfs2; GINS complex subunit 2

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Jurkat
Observed Size 21 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 51659 Human GINS2

Swiss-port # Q9Y248 Human DNA replication complex GINS protein PSF2

Gene Symbol GINS2
Gene Full Name GINS complex subunit 2 (Psf2 homolog)
Background The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Function The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 21 kDa