ARG58804
anti-GJA5 / Connexin 40 antibody
anti-GJA5 / Connexin 40 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GJA5 / Connexin 40 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Predict Reactivity | Hu, Hm |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GJA5 / Connexin 40 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 341-358 of Human Connexin 40 (KRRLSKASSKARSDDLSV). |
| Conjugation | Un-conjugated |
| Alternate Names | Cx40; CX40; Connexin-40; Gap junction alpha-5 protein; ATFB11 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GJA5 |
| Gene Full Name | gap junction protein, alpha 5, 40kDa |
| Background | This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008] |
| Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. [UniProt] |
| Calculated MW | 40 kDa |
