ARG55324
anti-GLUD1 + GLUD2 antibody
anti-GLUD1 + GLUD2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GLUD1 + GLUD2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Specificity | This antibody was designed to react C-terminal of GLUD2 protein and it is expected to recognize both GLUD1 and GLUD2 proteins based on sequence homology analysis result |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GLUD1 + GLUD2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein corresponding to aa. 319-558 of Human GLUD2 (NP_036216.2) |
| Conjugation | Un-conjugated |
| Alternate Names | GDH1; GDH 1; Glutamate dehydrogenase 1, mitochondrial; GDH; GLUD; EC 1.4.1.3; Glutamate dehydrogenase 2, mitochondrial; GLUDP1; EC 1.4.1.3; GDH 2; GDH2 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | MCF7 |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P49448 Human Glutamate dehydrogenase 2, mitochondrial |
|---|---|
| Gene Symbol | GLUD2 |
| Gene Full Name | glutamate dehydrogenase 2 |
| Background | The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.[provided by RefSeq, Jan 2010] |
| Function | Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 61 kDa |
| PTM | Stoichiometry shows that ADP-ribosylation occurs in one subunit per catalytically active homohexamer. |
