ARG22879

anti-GLUT4 antibody [1F8]

anti-GLUT4 antibody [1F8] for IHC-Frozen sections,ICC/IF,Immunoprecipitation,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Rat,Mouse,Monkey,Rabbit,Human,Pig

Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody; Glucose uptake: Insulin Receptor Dependent Pathway Study antibody

Overview

Product Description Mouse Monoclonal antibody [1F8] recognizes GLUT4
Tested Reactivity Hu, Ms, Rat, Mk, Pig, Rb
Species Does Not React With Dog
Tested Application ICC/IF, IHC-Fr, IHC-P, IP, WB
Host Mouse
Clonality Monoclonal
Clone 1F8
Isotype IgG1
Target Name GLUT4
Antigen Species Rat
Immunogen Partially purified vesicles containing insulin-responsive glucose transporter 4.
Conjugation Un-conjugated
Alternate Names Glucose transporter type 4, insulin-responsive; GLUT4; GLUT-4; Solute carrier family 2, facilitated glucose transporter member 4

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IFAssay-dependent
IHC-FrAssay-dependent
IHC-PAssay-dependent
IPAssay-dependent
WB1:100 - 1:1000
Application Note IHC-P: This product requires enzyme mediated antigen retrieval prior to staining of parrafin sections. Proteinase K is recomended for this purpose.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% Sodium azide
Preservative 0.09% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 20528 Mouse SLC2A4

GeneID: 25139 Rat SLC2A4

GeneID: 6517 Human SLC2A4

Gene Symbol Slc2a4
Gene Full Name solute carrier family 2 (facilitated glucose transporter), member 4
Background This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
Function Insulin-regulated facilitative glucose transporter. [UniProt]
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody; Glucose uptake: Insulin Receptor Dependent Pathway Study antibody
Calculated MW 55 kDa
PTM Sumoylated.