ARG21498
anti-GM-CSF antibody [MP1-22E9]
anti-GM-CSF antibody [MP1-22E9] for ELISA,ELISPOT,Flow cytometry,IHC-Frozen sections,ICC/IF,Western blot,Neutralizing and Mouse
Publication1
Overview
| Product Description | Rat Monoclonal antibody [MP1-22E9] recognizes GM-CSF |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA, ELISPOT, FACS, ICC/IF, IHC-Fr, Neut, WB |
| Specificity | Mouse GM-CSF. |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | MP1-22E9 |
| Isotype | IgG2a, kappa |
| Target Name | GM-CSF |
| Antigen Species | Mouse |
| Immunogen | COS-expressed mouse GM-CSF |
| Conjugation | Un-conjugated |
| Alternate Names | GM-CSF; Granulocyte-macrophage colony-stimulating factor; CSF; GMCSF; Molgramostin; Colony-stimulating factor; Sargramostim |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | BBS (pH 8.2) |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P01587 Mouse Granulocyte-macrophage colony-stimulating factor |
|---|---|
| Gene Symbol | CSF2 |
| Gene Full Name | colony stimulating factor 2 (granulocyte-macrophage) |
| Background | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008] |
| Function | Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. [UniProt] |
| Highlight | Related products: GM-CSF antibodies; GM-CSF ELISA Kits; GM-CSF Duos / Panels; GM-CSF recombinant proteins; Anti-Rat IgG secondary antibodies; Related news: HMGB1 in inflammation Inflammatory Cytokines |
| Calculated MW | 16 kDa |
Specific References
Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein.
FACS / Mouse
