ARG66575
anti-GNAT1 antibody
anti-GNAT1 antibody for IHC-Frozen sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GNAT1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-Fr, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GNAT1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide between aa. 40-120 of Human GNAT1. |
| Conjugation | Un-conjugated |
| Alternate Names | GBT1; GNATR; CSNB1G; CSNBAD3; Guanine nucleotide-binding protein G(t) subunit alpha-1; Transducin alpha-1 chain |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P11488 Human Guanine nucleotide-binding protein G(t) subunit alpha-1 Swiss-port # P20612 Mouse Guanine nucleotide-binding protein G(t) subunit alpha-1 |
|---|---|
| Gene Symbol | GNAT1 |
| Gene Full Name | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 |
| Background | Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009] |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase. [UniProt] |
| Cellular Localization | Cell projection, cilium, photoreceptor outer segment. Membrane; Peripheral membrane protein. [UniProt] |
| Calculated MW | 40 kDa |
