ARG58860
anti-GNRH1 / Progonadoliberin 1 antibody
anti-GNRH1 / Progonadoliberin 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GNRH1 / Progonadoliberin 1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GNRH1 / Progonadoliberin 1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 24-92 of Human GNRH1 / Progonadoliberin 1 (NP_001076580.1). |
| Conjugation | Un-conjugated |
| Alternate Names | GnRH-I; Progonadoliberin-1; GNRH; LH-RH I; LNRH; LHRH; GnRH-associated peptide I; Luliberin I; Luteinizing hormone-releasing hormone I; HH12; Gonadotropin-releasing hormone I; Gonadorelin; Progonadoliberin I; GRH; Gonadoliberin I |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | SH-SY5Y | ||||||
| Observed Size | 12 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GNRH1 |
| Gene Full Name | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| Background | The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012] |
| Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 10 kDa |
