ARG41962
anti-GOLGA4 / Golgin 245 antibody
anti-GOLGA4 / Golgin 245 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Goat Polyclonal antibody recognizes GOLGA4 / Golgin 245 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | IHC-P |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GOLGA4 / Golgin 245 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the C-terminus of Human Golgin 245. (C-DDQTQKILERED) (NP_002069.2) |
| Conjugation | Un-conjugated |
| Alternate Names | GCP2; CRPF46; Trans-Golgi p230; Golgin subfamily A member 4; GOLG; MU-RMS-40.18; p230; Golgin-245; 256 kDa golgin; Protein 72.1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Ammonium sulphate precipitation followed by affinity purification with immunogen. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GOLGA4 |
| Gene Full Name | golgin A4 |
| Background | The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010] |
| Function | May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. [UniProt] |
| Cellular Localization | Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane. [UniProt] |
| Calculated MW | 261 kDa |
