ARG42046

anti-GON7 / C14orf142 antibody

anti-GON7 / C14orf142 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes GON7 / C14orf142
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog, Hrs, Pig
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GON7 / C14orf142
Antigen Species Human
Immunogen Synthetic peptide around the C-terminal region of Human GON7 / C14orf142. (within the following region: LVQGE VQHRV AAAPD EDLDG DDEDD AEDEN NIDNR TNFDG PSAKR PKTPS)
Conjugation Un-conjugated
Alternate Names PNAS-127; C14orf142; chromosome 14 open reading frame 142

Application Instructions

Predict Reactivity Note Predicted Homology Based On Immunogen Sequence: Cow: 86%; Dog: 86%; Horse: 86%; Mouse: 91%; Pig: 79%; Rat: 91%
Application Suggestion
Tested Application Dilution
WB2 - 10 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Jurkat
Observed Size ~ 11 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS, 0.09% (w/v) Sodium azide and 2% Sucrose.
Preservative 0.09% (w/v) Sodium azide
Stabilizer 2% Sucrose
Concentration Batch dependent: 0.5 - 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 84520 Human GON7

Swiss-port # Q9BXV9 Human EKC/KEOPS complex subunit GON7

Gene Symbol GON7
Gene Full Name GON7 subunit of KEOPS complex
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit OSGEP in the complex. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 11 kDa