ARG42046
anti-GON7 / C14orf142 antibody
anti-GON7 / C14orf142 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GON7 / C14orf142 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Hrs, Pig |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GON7 / C14orf142 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the C-terminal region of Human GON7 / C14orf142. (within the following region: LVQGE VQHRV AAAPD EDLDG DDEDD AEDEN NIDNR TNFDG PSAKR PKTPS) |
| Conjugation | Un-conjugated |
| Alternate Names | PNAS-127; C14orf142; chromosome 14 open reading frame 142 |
Application Instructions
| Predict Reactivity Note | Predicted Homology Based On Immunogen Sequence: Cow: 86%; Dog: 86%; Horse: 86%; Mouse: 91%; Pig: 79%; Rat: 91% | ||||
|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Jurkat | ||||
| Observed Size | ~ 11 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| Preservative | 0.09% (w/v) Sodium azide |
| Stabilizer | 2% Sucrose |
| Concentration | Batch dependent: 0.5 - 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GON7 |
| Gene Full Name | GON7 subunit of KEOPS complex |
| Function | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit OSGEP in the complex. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 11 kDa |
