ARG59523
anti-GORASP2 antibody
anti-GORASP2 antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GORASP2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GORASP2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 353-452 of Human GORASP2 (NP_056345.3). |
| Conjugation | Un-conjugated |
| Alternate Names | GRS2; Golgi reassembly-stacking protein of 55 kDa; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein 2; GRASP55; p59 |
Application Instructions
| Predict Reactivity Note | Rat | ||||||
|---|---|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Mouse liver and HeLa | ||||||
| Observed Size | 57 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q99JX3 Mouse Golgi reassembly-stacking protein 2 Swiss-port # Q9H8Y8 Human Golgi reassembly-stacking protein 2 |
|---|---|
| Gene Symbol | GORASP2 |
| Gene Full Name | golgi reassembly stacking protein 2, 55kDa |
| Background | This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
| Function | Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. [UniProt] |
| Cellular Localization | Golgi apparatus membrane; Lipid-anchor. Membrane; Peripheral membrane protein. Membrane; Lipid-anchor. [UniProt] |
| Calculated MW | 47 kDa |
| PTM | Myristoylated. Myristoylation is essential for the Golgi targeting (By similarity). Palmitoylated. Phosphorylated in mitotic cells. [UniProt] |
