ARG41042
anti-GPR68 / OGR1 antibody
anti-GPR68 / OGR1 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GPR68 / OGR1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GPR68 / OGR1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 276-365 of Human GPR68 (NP_003476.3). |
| Conjugation | Un-conjugated |
| Alternate Names | G-protein coupled receptor 68; Sphingosylphosphorylcholine receptor; Ovarian cancer G-protein coupled receptor 1; GPR12A; OGR-1; OGR1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HL-60 | ||||
| Observed Size | 41 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q15743 Human Ovarian cancer G-protein coupled receptor 1 Swiss-port # Q8BFQ3 Mouse Ovarian cancer G-protein coupled receptor 1 |
|---|---|
| Gene Symbol | GPR68 |
| Gene Full Name | G protein-coupled receptor 68 |
| Function | Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity). [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 41 kDa |
