ARG56169
anti-GPR77 / C5L2 antibody
anti-GPR77 / C5L2 antibody for Western blot and Human,Primates
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GPR77 / C5L2 |
|---|---|
| Tested Reactivity | Hu, NHuPrm |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GPR77 / C5L2 |
| Antigen Species | Human |
| Immunogen | A recombinant protein fragment from the N-terminal region of human GPR77 / C5L2. |
| Conjugation | Un-conjugated |
| Alternate Names | G-protein coupled receptor 77; C5a anaphylatoxin chemotactic receptor 2; GPR77; Complement component 5a receptor 2; GPF77; C5L2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 0.1 mg/ml BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9P296 Human C5a anaphylatoxin chemotactic receptor 2 |
|---|---|
| Gene Symbol | C5AR2 |
| Gene Full Name | complement component 5a receptor 2 |
| Background | This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
| Function | Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. [UniProt] |
| Calculated MW | 36 kDa |
