ARG64151

anti-GPX3 antibody

anti-GPX3 antibody for IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Pig

Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes GPX3
Tested Reactivity Hu, Ms, Pig
Predict Reactivity Dog, Rat
Tested Application IHC-Fr, IHC-P, WB
Specificity This antibody may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name GPX3
Antigen Species Human
Immunogen C-NQFGKQEPGENSE
Conjugation Un-conjugated
Alternate Names Plasma glutathione peroxidase; Extracellular glutathione peroxidase; GPx-P; GPx-3; EC 1.11.1.9; Glutathione peroxidase 3; GSHPx-3; GSHPx-P

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-Fr20 µg/ml
IHC-P5 µg/ml
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 14778 Mouse GPX3

GeneID: 2878 Human GPX3

Swiss-port # P22352 Human Glutathione peroxidase 3

Swiss-port # P46412 Mouse Glutathione peroxidase 3

Background This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 26 kDa
PTM The N-terminus is blocked.