ARG58916

anti-GSTT1 antibody

anti-GSTT1 antibody for Flow cytometry,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes GSTT1
Tested Reactivity Hu
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GSTT1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 7-34 of Human GSTT1.
Conjugation Un-conjugated
Alternate Names Glutathione S-transferase theta-1; EC 2.5.1.18; GST class-theta-1; Glutathione transferase T1-1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:10 - 1:50
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human lung

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2952 Human GSTT1

Swiss-port # P30711 Human Glutathione S-transferase theta-1

Gene Symbol GSTT1
Gene Full Name glutathione S-transferase theta 1
Background The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide. [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Calculated MW 27 kDa