ARG59606

anti-GUCY2F antibody

anti-GUCY2F antibody for Western blot and Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes GUCY2F
Tested Reactivity Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GUCY2F
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 250-460 of Human GUCY2F (NP_001513.2).
Conjugation Un-conjugated
Alternate Names ROS-GC2; CYGF; Rod outer segment membrane guanylate cyclase 2; Guanylate cyclase F; Retinal guanylyl cyclase 2; GC-F; GUC2F; GUC2DL; EC 4.6.1.2; RETGC-2; Guanylate cyclase 2F, retinal

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse eye
Observed Size 125 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 245650 Mouse GUCY2F

Swiss-port # Q5SDA5 Mouse Retinal guanylyl cyclase 2

Gene Symbol GUCY2F
Gene Full Name guanylate cyclase 2F, retinal
Background The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008]
Function Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 125 kDa
PTM There are 9 conserved cysteine residues in sensory guanylate cyclases, 6 in the extracellular domain, which may be involved in intra- or interchain disulfide bonds. [UniProt]