ARG64049

anti-Gelsolin antibody

anti-Gelsolin antibody for Flow cytometry,Western blot and Human

Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes Gelsolin
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog
Tested Application FACS, WB
Specificity This antibody is expected to recognize both reported isoforms (NP_000168.1 and NP_937895.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name Gelsolin
Antigen Species Human
Immunogen C-PRLKDKKMDAHP
Conjugation Un-conjugated
Alternate Names ADF; Actin-depolymerizing factor; Brevin; AGEL; Gelsolin

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µg/ml
WB0.1 - 2 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2934 Human GSN

Swiss-port # P06396 Human Gelsolin

Background The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area Signaling Transduction antibody
Calculated MW 86 kDa
PTM Phosphorylation on Tyr-86, Tyr-409, Tyr-465, Tyr-603 and Tyr-651 in vitro is induced in presence of phospholipids.