ARG55692

anti-Glutathione Synthetase antibody

anti-Glutathione Synthetase antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes Glutathione Synthetase
Tested Reactivity Hu, Ms
Predict Reactivity Bov, Rat, Mk
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Glutathione Synthetase
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 372-400 (C-terminus) of Human Glutathione Synthetase.
Conjugation Un-conjugated
Alternate Names Glutathione synthase; GSH synthetase; EC 6.3.2.3; HEL-S-64p; Glutathione synthetase; GSHS; HEL-S-88n; GSH-S

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:25
IHC-P1:25
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control MDA-MB-453

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 14854 Mouse GSS

GeneID: 2937 Human GSS

Swiss-port # P48637 Human Glutathione synthetase

Swiss-port # P51855 Mouse Glutathione synthetase

Gene Symbol GSS
Gene Full Name glutathione synthetase
Background Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq, Jul 2008]
Calculated MW 52 kDa