ARG58893
anti-Glycine Receptor alpha 2 antibody
anti-Glycine Receptor alpha 2 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Glycine Receptor alpha 2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Glycine Receptor alpha 2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 350-420 of Human Glycine Receptor alpha 2 (NP_002054.1). |
| Conjugation | Un-conjugated |
| Alternate Names | GLR; Glycine receptor subunit alpha-2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse spinal cord | ||||
| Observed Size | 52 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GLRA2 |
| Gene Full Name | glycine receptor, alpha 2 |
| Background | The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010] |
| Function | The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). [UniProt] |
| Cellular Localization | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. [UniProt] |
| Calculated MW | 52 kDa |
