ARG64079

anti-GnRHR / GnRH Receptor antibody

anti-GnRHR / GnRH Receptor antibody for Western blot and Human

Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes GnRHR / GnRH Receptor
Tested Reactivity Hu
Predict Reactivity Dog
Tested Application WB
Specificity This antibody is expected to recognise both reported isoforms (NP_000397.1; NP_001012781.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name GnRHR / GnRH Receptor
Antigen Species Human
Immunogen C-QKWTQKKEKGK
Conjugation Un-conjugated
Alternate Names GRHR; HH7; LRHR; LHRHR; Gonadotropin-releasing hormone receptor; GnRH receptor; GNRHR1; GnRH-R

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.5 - 1.5 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2798 Human GNRHR

Swiss-port # P30968 Human Gonadotropin-releasing hormone receptor

Background This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
Research Area Neuroscience antibody
Calculated MW 38 kDa