ARG59601
anti-Guanylate Cyclase alpha antibody
anti-Guanylate Cyclase alpha antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Guanylate Cyclase alpha |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Guanylate Cyclase alpha |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-120 of Human Guanylate Cyclase alpha (NP_000847.2). |
| Conjugation | Un-conjugated |
| Alternate Names | Soluble guanylate cyclase large subunit; GC-SA3; MYMY6; GUC1A3; Guanylate cyclase soluble subunit alpha-3; GUCY1A1; GUCA3; GCS-alpha-1; GUCSA3; EC 4.6.1.2; GCS-alpha-3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Rat kidney, Mouse brain and A549 | ||||||
| Observed Size | 77 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q02108 Human Guanylate cyclase soluble subunit alpha-3 Swiss-port # Q9ERL9 Mouse Guanylate cyclase soluble subunit alpha-3 |
|---|---|
| Gene Symbol | GUCY1A3 |
| Gene Full Name | guanylate cyclase 1, soluble, alpha 3 |
| Background | Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 77 kDa |
