ARG56512
anti-Guanylate Cyclase beta 1 antibody
anti-Guanylate Cyclase beta 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat,Bovine
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Guanylate Cyclase beta 1 |
|---|---|
| Tested Reactivity | Hu, Rat, Bov |
| Tested Application | IHC-P, WB |
| Specificity | This antibody does not react to guanylate cyclase α1 subunit. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Guanylate Cyclase beta 1 |
| Antigen Species | Rat |
| Immunogen | Synthetic peptide around aa. 188-207 of Rat Guanylate Cyclase beta1 (soluble). (EDFYEDLDRFEENGTQDSR; last D=E in Human and Bovine) |
| Conjugation | Un-conjugated |
| Alternate Names | GC-S-beta-1; GUC1B3; GUCSB3; Soluble guanylate cyclase small subunit; GCS-beta-1; GUCY1B1; GCS-beta-3; GUCB3; EC 4.6.1.2; Guanylate cyclase soluble subunit beta-3; GC-SB3; Guanylate cyclase soluble subunit beta-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4) and 5 mg/ml BSA. |
| Stabilizer | 5 mg/ml BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Gucy1b3 |
| Gene Full Name | guanylate cyclase 1, soluble, beta 3 |
| Background | This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| Calculated MW | 71 kDa |
