ARG64362

anti-HADH / HADHSC antibody

anti-HADH / HADHSC antibody for Western blot and Human

Cancer antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes HADH / HADHSC
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name HADH / HADHSC
Antigen Species Human
Immunogen C-YERGDASKEDID
Conjugation Un-conjugated
Alternate Names Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; HAD; EC 1.1.1.35; HADHSC; HHF4; HCDH; SCHAD; Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HADH1; MSCHAD

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.01 - 0.03 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3033 Human HADH

Swiss-port # Q16836 Human Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

Background This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]
Research Area Cancer antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 34 kDa
PTM Succinylation at Lys-81, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5 (By similarity).