ARG42207

anti-HHLA2 / B7-H7 antibody

anti-HHLA2 / B7-H7 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes HHLA2 / B7-H7
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HHLA2 / B7-H7
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 30-200 of Human HHLA2 / B7-H7 (NP_009003.1).
Conjugation Un-conjugated
Alternate Names B7H7; HERV-H LTR-associating protein 2; B7-H7; Human endogenous retrovirus-H long terminal repeat-associating protein 2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11148 Human HHLA2

Swiss-port # Q9UM44 Human HERV-H LTR-associating protein 2

Gene Symbol HHLA2
Gene Full Name HERV-H LTR-associating 2
Background This gene encodes a protein ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Function Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 47 kDa