ARG64902
anti-HIPPI antibody
anti-HIPPI antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes HIPPI |
|---|---|
| Tested Reactivity | Hu, Ms |
| Predict Reactivity | Cow, Rat |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HIPPI |
| Antigen Species | Human |
| Immunogen | C-EQPQEYDDPNATISN |
| Conjugation | Un-conjugated |
| Alternate Names | HIPPI; ESRRBL1; Dermal papilla-derived protein 8; Intraflagellar transport protein 57 homolog; HIP1-interacting protein; MHS4R2; Estrogen-related receptor beta-like protein 1 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8BXG3 Mouse Intraflagellar transport protein 57 homolog Swiss-port # Q9NWB7 Human Intraflagellar transport protein 57 homolog |
|---|---|
| Gene Symbol | IFT57 |
| Gene Full Name | intraflagellar transport 57 |
| Function | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. [UniProt] |
| Research Area | Neuroscience antibody |
| Calculated MW | 49 kDa |
