ARG42443
anti-HLA ABCE antibody [TP25.99SF]
anti-HLA ABCE antibody [TP25.99SF] for Flow cytometry,Western blot,IHC-Frozen sections and Human
Overview
| Product Description | Mouse Monoclonal antibody [TP25.99SF] recognizes HLA ABCE |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-Fr, WB |
| Specificity | The mouse monoclonal antibody TP25.99SF recognizes an extracellular epitope on HLA-ABC and HLA-E molecules, but not HLA-G. It can be used for discrimination between HLA-G and other HLA-class I antigens. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | TP25.99SF |
| Isotype | IgG1 |
| Target Name | HLA ABCE |
| Antigen Species | Human |
| Immunogen | IFN-gamma-treated Human melanoma cells Colo 38. |
| Conjugation | Un-conjugated |
| Alternate Names | MHC class I antigen A*1; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS and 15 mM Sodium azide. |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P30443 Human HLA class I histocompatibility antigen, A-1 alpha chain |
|---|---|
| Gene Symbol | HLA-A |
| Gene Full Name | major histocompatibility complex, class I, A |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
| PTM | Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity). [UniProt] |
