ARG56219
anti-HMGA2 / HMGI-C antibody
anti-HMGA2 / HMGI-C antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes HMGA2 / HMGI-C |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HMGA2 / HMGI-C |
| Antigen Species | Mouse |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 72-105 (C-terminus) of Mouse HMGA2. |
| Conjugation | Un-conjugated |
| Alternate Names | 9430083A20Rik; Hmgic; HMGI-C; High mobility group AT-hook protein 2; pg; pygmy; High mobility group protein HMGI-C |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | HepG2 |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) sodium azide. |
| Preservative | 0.09% (W/V) sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P52926 Human High mobility group protein HMGI-C Swiss-port # P52927 Mouse High mobility group protein HMGI-C |
|---|---|
| Gene Symbol | Hmga2 |
| Gene Full Name | high mobility group AT-hook 2 |
| Function | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. [UniProt] |
| Cellular Localization | Nucleus. |
| Calculated MW | 12 kDa |
| PTM | Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2 (By similarity). |
