ARG43806
anti-HMGN5 antibody
anti-HMGN5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes HMGN5 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HMGN5 |
| Antigen Species | Human |
| Immunogen | Recombinant protein corresponding to human HMGN5 |
| Conjugation | Un-conjugated |
| Alternate Names | HMGN5; High Mobility Group Nucleosome Binding Domain 5; NSBP1; High Mobility Group Nucleosome-Binding Domain-Containing Protein 5; Nucleosomal Binding Protein 1; Nucleosome-Binding Protein 1; High-Mobility Group Nucleosome Binding Domain 5; NBP-45 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | MDA-MB-231 | ||||||
| Observed Size | 32 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen |
| Buffer | pH 7.4 PBS, 0.05% NaN3, and 40% Glycerol |
| Concentration | 0.3 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P82970 Human High mobility group nucleosome-binding domain-containing protein 5 |
|---|---|
| Gene Symbol | HMGN5 |
| Gene Full Name | High Mobility Group Nucleosome Binding Domain 5 |
| Background | This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009] |
| Function | Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. ( HMGN5_HUMAN,P82970 ) |
| Cellular Localization | Nucleus |
| Calculated MW | 32 kDa |
| PTM | Isopeptide bond; Phosphoprotein; Ubl conjugation |
