ARG66738
anti-HSD17B11 antibody
anti-HSD17B11 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes HSD17B11 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HSD17B11 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide between aa. 71-120 of Human HSD17B11. |
| Conjugation | Un-conjugated |
| Alternate Names | Cutaneous T-cell lymphoma-associated antigen HD-CL-03; CTCL-associated antigen HD-CL-03; 17-beta-hydroxysteroid dehydrogenase 11; retSDR2; 17-beta-HSD XI; Short chain dehydrogenase/reductase family 16C member 2; 17-beta-HSD 11; SDR16C2; 17betaHSD11; Dehydrogenase/reductase SDR family member 8; PAN1B; 17-beta-hydroxysteroid dehydrogenase XI; 17BHSD11; RETSDR2; Estradiol 17-beta-dehydrogenase 11; 17bHSD11; 17-BETA-HSD11; DHRS8; 17-BETA-HSDXI; Retinal short-chain dehydrogenase/reductase 2; EC 1.1.1.62; 17betaHSDXI |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | 293 and Raw264.7 | ||||
| Observed Size | 32 ~ 34 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8NBQ5 Human Estradiol 17-beta-dehydrogenase 11 Swiss-port # Q9EQ06 Mouse Estradiol 17-beta-dehydrogenase 11 |
|---|---|
| Gene Symbol | HSD17B11 |
| Gene Full Name | hydroxysteroid (17-beta) dehydrogenase 11 |
| Background | Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009] |
| Function | Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 33 kDa |
