ARG22396

anti-HVEM / TR2 antibody [CW2]

anti-HVEM / TR2 antibody [CW2] for ICC/IF,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody [CW2] recognizes HVEM / TR2
Tested Reactivity Hu
Tested Application ICC/IF, WB
Host Mouse
Clonality Monoclonal
Clone CW2
Isotype IgG1, kappa
Target Name HVEM / TR2
Antigen Species Human
Immunogen Human HVEM / TR2
Conjugation Un-conjugated
Alternate Names Herpes virus entry mediator A; HVEM; Tumor necrosis factor receptor-like 2; HVEA; CD antigen CD270; CD270; Tumor necrosis factor receptor superfamily member 14; LIGHTR; HveA; Herpesvirus entry mediator A; ATAR; TR2

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IFAssay-dependent
WB10 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4)
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8764 Human TNFRSF14

Swiss-port # Q92956 Human Tumor necrosis factor receptor superfamily member 14

Gene Symbol TNFRSF14
Gene Full Name tumor necrosis factor receptor superfamily, member 14
Background This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Function Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. [UniProt]
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HVEM antibodies; HVEM ELISA Kits; Anti-Mouse IgG secondary antibodies;
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Calculated MW 30 kDa
PTM N-glycosylated.