ARG22207
anti-Hsp 47 antibody [1C4-1A6]
anti-Hsp 47 antibody [1C4-1A6] for ICC/IF,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1C4-1A6] recognizes Hsp 47 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1C4-1A6 |
| Isotype | IgG1, kappa |
| Target Name | Hsp 47 |
| Antigen Species | Human |
| Immunogen | Full length Human HSP47 |
| Conjugation | Un-conjugated |
| Alternate Names | Serpin H1; AsTP3; gp46; CBP2; CBP1; HSP47; RA-A47; Collagen-binding protein; PPROM; PIG14; 47 kDa heat shock protein; OI10; Rheumatoid arthritis-related antigen RA-A47; Cell proliferation-inducing gene 14 protein; Colligin; SERPINH2; Arsenic-transactivated protein 3 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SERPINH1 |
| Gene Full Name | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| Background | This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011] |
| Function | Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. [UniProt] |
| Cellular Localization | Endoplasmic Reticulum, Endoplasmic reticulum lumen |
| Calculated MW | 46 kDa |
