ARG56243

anti-Hsp 47 antibody

anti-Hsp 47 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes Hsp 47
Tested Reactivity Hu, Ms
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Hsp 47
Antigen Species Human
Immunogen Recombinant protein of Human Hsp47
Conjugation Un-conjugated
Alternate Names Serpin H1; AsTP3; gp46; CBP2; CBP1; HSP47; RA-A47; Collagen-binding protein; PPROM; PIG14; 47 kDa heat shock protein; OI10; Rheumatoid arthritis-related antigen RA-A47; Cell proliferation-inducing gene 14 protein; Colligin; SERPINH2; Arsenic-transactivated protein 3

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control U251

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12406 Mouse SERPINH1

GeneID: 871 Human SERPINH1

Swiss-port # P19324 Mouse Serpin H1

Swiss-port # P50454 Human Serpin H1

Gene Symbol SERPINH1
Gene Full Name serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Background This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]
Function Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. [UniProt]
Calculated MW 46 kDa