ARG67108

anti-IARS2 antibody

anti-IARS2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Monkey

Overview

Product Description Rabbit Polyclonal antibody recognizes IARS2
Tested Reactivity Hu, Ms, Mk
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name IARS2
Antigen Species Human
Immunogen Human IARS2 Synthesized peptide
Conjugation Un-conjugated
Alternate Names IARS2; Isoleucyl-TRNA Synthetase 2, Mitochondrial; Isoleucine TRNA Ligase 2, Mitochondrial; Isoleucine--TRNA Ligase, Mitochondrial; EC 6.1.1.5; FLJ10326; Isoleucine-TRNA Synthetase 2, Mitochondrial; Isoleucyl-TRNA Synthetase, Mitochondrial; Mitochondrial Isoleucine TRNA Synthetase; Isoleucyl-TRNA Synthetase; EC 6.1.1; CAGSSS; ILERS; IleRS

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:200-1:1000
IHC-P1:100-1:300
WB1:500-2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol and 0.5% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 381314 Mouse IARS2

GeneID: 55699 Human IARS2

Swiss-port # Q8BIJ6 Mouse Isoleucine--tRNA ligase, mitochondrial

Swiss-port # Q9NSE4 Human Isoleucine--tRNA ligase, mitochondrial

Gene Symbol IARS2
Gene Full Name Isoleucyl-TRNA Synthetase 2, Mitochondrial
Background Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family.
Function Aminoacyl-tRNA synthetase that catalyzes the specific attachment of isoleucine to its cognate tRNA (tRNA(Ile)).
Cellular Localization Mitochondrion
Calculated MW 114 kDa
PTM Acetylation