ARG56664
anti-IGF1 antibody
anti-IGF1 antibody for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Neutralizing,Western blot and Human,Mouse,Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes IGF1 |
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Tested Reactivity | Hu, Ms, Rat |
Tested Application | ELISA, IHC-P, Neut, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | IGF1 |
Antigen Species | Human |
Immunogen | E.coli derived Recombinant Human IGF1. (GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA) |
Conjugation | Un-conjugated |
Alternate Names | MGF; Insulin-like growth factor I; Mechano growth factor; Somatomedin-C; IGFI; IGF-I |
Application Instructions
Application Suggestion |
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Application Note | Antigen retrieval for IHC-P: Boil the paraffin sections in 10 mM citrate buffer (pH 6.0) for 30 minutes. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS (pH 7.2) |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | IGF1 |
Gene Full Name | insulin-like growth factor 1 (somatomedin C) |
Background | The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015] |
Function | The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. [UniProt] |
Highlight | Related products: IGF1 antibodies; IGF1 ELISA Kits; IGF1 Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: A new role of fat – factory of circulating miRNAs |
Calculated MW | 22 kDa |