ARG65273
anti-IGF2BP1 / IMP1 antibody
anti-IGF2BP1 / IMP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Gene Regulation antibody
Overview
Product Description | Goat Polyclonal antibody recognizes IGF2BP1 / IMP1. |
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Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat, Cow, Dog |
Tested Application | IHC-P, WB |
Specificity | This antibody is expected to recognize both reported isoforms (NP_006537.3; NP_001153895.1). |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | IGF2BP1 / IMP1 |
Antigen Species | Human |
Immunogen | C-EKVFAEHKISYSGQ |
Conjugation | Un-conjugated |
Alternate Names | VICKZ1; CRDBP; IMP1; IMP-1; ZBP-1; ZBP1; CRD-BP; VICKZ family member 1; IGF2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; Zipcode-binding protein 1; Coding region determinant-binding protein; Insulin-like growth factor 2 mRNA-binding protein 1 |
Application Instructions
Application Suggestion |
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Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9NZI8 Human Insulin-like growth factor 2 mRNA-binding protein 1 |
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Background | This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
Research Area | Gene Regulation antibody |
Calculated MW | 63 kDa |
PTM | Phosphorylated. Phosphorylation may impair association with ACTB mRNA and hence abolishes translational repression (By similarity). |