ARG65273

anti-IGF2BP1 / IMP1 antibody

anti-IGF2BP1 / IMP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Gene Regulation antibody

Overview

Product Description Goat Polyclonal antibody recognizes IGF2BP1 / IMP1.
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog
Tested Application IHC-P, WB
Specificity This antibody is expected to recognize both reported isoforms (NP_006537.3; NP_001153895.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name IGF2BP1 / IMP1
Antigen Species Human
Immunogen C-EKVFAEHKISYSGQ
Conjugation Un-conjugated
Alternate Names VICKZ1; CRDBP; IMP1; IMP-1; ZBP-1; ZBP1; CRD-BP; VICKZ family member 1; IGF2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; Zipcode-binding protein 1; Coding region determinant-binding protein; Insulin-like growth factor 2 mRNA-binding protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 5 µg/ml
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10642 Human IGF2BP1

Swiss-port # Q9NZI8 Human Insulin-like growth factor 2 mRNA-binding protein 1

Background This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Research Area Gene Regulation antibody
Calculated MW 63 kDa
PTM Phosphorylated. Phosphorylation may impair association with ACTB mRNA and hence abolishes translational repression (By similarity).