ARG64343
anti-IGFBP3 antibody
anti-IGFBP3 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody
Overview
Product Description | Goat Polyclonal antibody recognizes IGFBP3 |
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Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat, Dog |
Tested Application | WB |
Specificity | This antibody is expected to recognise both reported isoforms (NP_001013416.1 and NP_000589.2). |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | IGFBP3 |
Antigen Species | Human |
Immunogen | C-RYKVDYESQSTDTQN |
Conjugation | Un-conjugated |
Alternate Names | IBP-3; IBP3; Insulin-like growth factor-binding protein 3; IGFBP-3; IGF-binding protein 3; BP-53 |
Application Instructions
Application Suggestion |
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Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # P17936 Human Insulin-like growth factor-binding protein 3 |
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Background | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody |
Calculated MW | 32 kDa |
PTM | Phosphorylated by FAM20C in the extracellular medium. |