ARG43812
anti-IGFBP5 antibody
anti-IGFBP5 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IGFBP5 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IGFBP5 |
| Antigen Species | Human |
| Immunogen | Recombinant protein within a.a. 20-280 of Human IGFBP5. |
| Conjugation | Un-conjugated |
| Protein Full Name | Insulin-like growth factor-binding protein 5 |
| Alternate Names | IBP5; IBP-5; IGF-binding protein 5; Insulin-like growth factor-binding protein 5; IGFBP-5 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | BT-474; U2OS | ||||
| Observed Size | 30-35 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | PBS (pH7.3) with 0.05% Proclin300 and 50% Glycerol. |
| Preservative | 0.05% Proclin300 |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P24593 Human Insulin-like growth factor-binding protein 5 |
|---|---|
| Gene Symbol | IGFBP5 |
| Gene Full Name | insulin-like growth factor binding protein 5 |
| Background | Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. [UniProt] |
| Cellular Localization | Secreted |
| Calculated MW | 31 kDa |
| PTM | Disulfide bond; Glycoprotein; Phosphoprotein |
