ARG42961
anti-IGLL1 / Lambda 5 antibody
anti-IGLL1 / Lambda 5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IGLL1 / Lambda 5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IGLL1 / Lambda 5 |
| Antigen Species | Human |
| Immunogen | Recombinant protein corresponding to L38-S213 of Human IGLL1 / Lambda 5. |
| Conjugation | Un-conjugated |
| Alternate Names | IGLL; Immunoglobulin omega polypeptide; 14.1; IGVPB; Immunoglobulin lambda-like polypeptide 1; Immunoglobulin-related protein 14.1; CD179 antigen-like family member B; IGLJ14.1; Ig lambda-5; CD antigen CD179b; AGM2; CD179b; IGO; IGL5; IGL1; VPREB2 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0) for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Observed Size | ~ 26 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P15814 Human Immunoglobulin lambda-like polypeptide 1 Swiss-port # P20764 Mouse Immunoglobulin lambda-like polypeptide 1 |
|---|---|
| Gene Symbol | IGLL1 |
| Gene Full Name | immunoglobulin lambda-like polypeptide 1 |
| Background | The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Critical for B-cell development. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 23 kDa |
