ARG65674
anti-IL10 antibody
anti-IL10 antibody for Neutralizing,Sandwich ELISA,Western blot and Mouse,Rat
Cancer antibody; Immune System antibody
Overview
| Product Description | Rat Monoclonal antibody recognizes IL10 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | Neut, WB, sELISA |
| Host | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | IL10 |
| Antigen Species | Mouse |
| Immunogen | E.coli derived recombinant mouse IL-10 |
| Conjugation | Un-conjugated |
| Alternate Names | IL10A; GVHDS; TGIF; IL-10; Cytokine synthesis inhibitory factor; CSIF; Interleukin-10 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Il10 |
| Gene Full Name | interleukin 10 |
| Background | This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015] |
| Function | Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. [UniProt] |
| Research Area | Cancer antibody; Immune System antibody |
| Calculated MW | 21 kDa |
