ARG40140
anti-IL11RA antibody
anti-IL11RA antibody for Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes IL11RA |
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Tested Reactivity | Hu |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | IL11RA |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide between aa. 372-403 of Human IL11RA. |
Conjugation | Un-conjugated |
Alternate Names | CRSDA; IL-11 receptor subunit alpha; IL-11RA; IL-11R subunit alpha; Interleukin-11 receptor subunit alpha; IL-11R-alpha |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | Jurkat |
Properties
Form | Liquid |
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Purification | Purification with Protein A and immunogen peptide. |
Buffer | PBS and 0.09% (W/V) Sodium azide. |
Preservative | 0.09% (W/V) Sodium azide. |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q14626 Human Interleukin-11 receptor subunit alpha |
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Gene Symbol | IL11RA |
Gene Full Name | interleukin 11 receptor, alpha |
Background | Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] |
Function | Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number. [UniProt] |
Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
Calculated MW | 45 kDa |