ARG55710

anti-IL13 Receptor alpha 1 antibody

anti-IL13 Receptor alpha 1 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes IL13 Receptor alpha 1
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name IL13 Receptor alpha 1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 207-238 (C-terminus) of Human IL13 Receptor alpha 1.
Conjugation Un-conjugated
Alternate Names CD antigen CD213a1; Interleukin-13 receptor subunit alpha-1; CD213A1; IL-13R-alpha-1; CT19; IL-13R subunit alpha-1; IL-13Ra; IL-13 receptor subunit alpha-1; IL-13RA1; Cancer/testis antigen 19; NR4

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Raji

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) sodium azide.
Preservative 0.09% (W/V) sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3597 Human IL13RA1

Swiss-port # P78552 Human Interleukin-13 receptor subunit alpha-1

Gene Symbol IL13RA1
Gene Full Name interleukin 13 receptor, alpha 1
Background The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]
Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein
Calculated MW 49 kDa