ARG56806
anti-IL17 / IL17A antibody (Biotin)
anti-IL17 / IL17A antibody (Biotin) for ELISA,Western blot and Human
Overview
Product Description | Biotin-conjugated Goat Polyclonal antibody recognizes IL17 / IL17A |
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Tested Reactivity | Hu |
Tested Application | ELISA, WB |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | IL17 / IL17A |
Antigen Species | Human |
Immunogen | E.coli derived Recombinant Human IL-17 (IL-17A). (MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA) |
Conjugation | Biotin |
Alternate Names | IL-17A; Interleukin-17A; IL-17; CTLA8; IL17; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8 |
Application Instructions
Application Suggestion |
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Application Note | Sandwich ELISA: Sandwich ELISA: Recommended antibody pairs in sandwich immunoassay for IL17 / IL17A (capture - detection): ARG56697 - ARG56806 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified by affinity chromatography. |
Buffer | PBS (pH 7.2) |
Concentration | 1 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | IL17A |
Gene Full Name | interleukin 17A |
Background | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008] |
Function | Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. [UniProt] |
Highlight | Related products: IL17 antibodies; IL17 ELISA Kits; IL17 recombinant proteins; Anti-Goat IgG secondary antibodies; Related news: HMGB1, a biomarker and therapeutic target in COVID-19 |
Calculated MW | 18 kDa |
PTM | Found both in glycosylated and nonglycosylated forms. |