ARG64945

anti-IL17RA antibody

anti-IL17RA antibody for Western blot and Rat

Immune System antibody

Overview

Product Description Goat Polyclonal antibody recognizes IL17RA
Tested Reactivity Rat
Predict Reactivity Ms
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name IL17RA
Antigen Species Mouse
Immunogen C-DQEKHGDDSKIN
Conjugation Un-conjugated
Alternate Names Interleukin-17 receptor A; IL-17RA; IL-17 receptor A; hIL-17R; CANDF5; CDw217; IL17R; CD217; CD antigen CD217

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol Il17ra
Gene Full Name interleukin 17 receptor A
Background Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
Function Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling (By similarity). [UniProt]
Research Area Immune System antibody
Calculated MW 96 kDa
PTM Glycosylated.