ARG22333

anti-IL2 Receptor beta antibody [5H4] (FITC)

anti-IL2 Receptor beta antibody [5H4] (FITC) for Flow cytometry and Mouse

Overview

Product Description FITC-conjugated Rat Monoclonal antibody [5H4] recognizes IL2 Receptor beta
Tested Reactivity Ms
Tested Application FACS
Specificity Mouse CD122
Host Rat
Clonality Monoclonal
Clone 5H4
Isotype IgG2a, kappa
Target Name IL2 Receptor beta
Antigen Species Mouse
Immunogen Rat myeloma YB2/0 transfected with truncated IL-2Rβ cDNA (YB2/0-mβt-28)
Conjugation FITC
Alternate Names P70-75; IL-2RB; IL-2 receptor subunit beta; p75; Interleukin-2 receptor subunit beta; CD122; CD antigen CD122; High affinity IL-2 receptor subunit beta; IL-2R subunit beta; p70-75; IL15RB

Application Instructions

Application Suggestion
Tested Application Dilution
FACS< 1 ug/10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer PBS and 0.1% Sodium azide.
Preservative 0.1% Sodium azide
Concentration 0.5 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 16185 Mouse IL2RB

Swiss-port # P16297 Mouse Interleukin-2 receptor subunit beta

Gene Symbol IL2RB
Gene Full Name interleukin 2 receptor, beta chain
Background The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]
Function Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. [UniProt]
Calculated MW 61 kDa