ARG21462

anti-IL2 antibody [JES6-5H4] (PE)

anti-IL2 antibody [JES6-5H4] (PE) for ELISA,Flow cytometry,ELISPOT,IHC-Frozen sections,Neutralizing and Mouse

Overview

Product Description PE-conjugated Rat Monoclonal antibody [JES6-5H4] recognizes IL2
Tested Reactivity Ms
Tested Application ELISA, ELISPOT, FACS, IHC-Fr, Neut
Specificity Mouse IL-2.
Host Rat
Clonality Monoclonal
Clone JES6-5H4
Isotype IgG2b, kappa
Target Name IL2
Antigen Species Mouse
Immunogen E. coli-expressed mouse IL-2
Conjugation PE
Alternate Names TCGF; IL-2; lymphokine; Interleukin-2; Aldesleukin; T-cell growth factor

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
ELISPOTAssay-dependent
FACS< 1 µg/10^6 cells
IHC-FrAssay-dependent
NeutAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer PBS, 0.1% Sodium azide and Sucrose.
Preservative 0.1% Sodium azide
Stabilizer Sucrose
Concentration 0.1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 16183 Mouse IL2

Swiss-port # P04351 Mouse Interleukin-2

Gene Symbol IL2
Gene Full Name interleukin 2
Background The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
Function Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. [UniProt]
Calculated MW 18 kDa