ARG23951
anti-IL2 antibody [SQab19135] (low endotoxin)
anti-IL2 antibody [SQab19135] (low endotoxin) for Neutralizing and Mouse
Overview
Product Description | Low endotoxin Rat Monoclonal antibody [SQab19135] recognizes IL2 |
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Tested Reactivity | Ms |
Tested Application | Neut |
Host | Rat |
Clonality | Monoclonal |
Clone | SQab19135 |
Isotype | IgG2a |
Target Name | IL2 |
Antigen Species | Mouse |
Immunogen | Recombinant Mouse IL2 protein. |
Conjugation | Un-conjugated |
Alternate Names | TCGF; IL-2; lymphokine; Interleukin-2; Aldesleukin; T-cell growth factor |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purification with Protein G. |
Purification Note | 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg. |
Buffer | PBS |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | IL2 |
Gene Full Name | interleukin 2 |
Background | The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008] |
Function | Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. [UniProt] |
Cellular Localization | Secreted. [UniProt] |
Calculated MW | 18 kDa |