ARG54647
anti-IL22 antibody
anti-IL22 antibody for ELISA,ICC/IF,Western blot and Human,Mouse,Rat
Immune System antibody; Signaling Transduction antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes IL22 |
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Tested Reactivity | Hu, Ms, Rat |
Tested Application | ELISA, ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | IL22 |
Antigen Species | Human |
Immunogen | Synthetic peptide (17 aa) within aa. 90-140 of Human IL-22 protein. |
Conjugation | Un-conjugated |
Alternate Names | Interleukin-22; zcyto18; IL-TIF; IL-22; IL-21; IL-D110; TIFa; ILTIF; TIFIL-23; IL-10-related T-cell-derived-inducible factor; Cytokine Zcyto18 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
Positive Control | HeLa Cell Lysate |
Properties
Form | Liquid |
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Purification | Immunogen affinity purified |
Buffer | PBS and 0.02% Sodium azide. |
Preservative | 0.02% Sodium azide |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | IL22 |
Gene Full Name | interleukin 22 |
Background | Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation (1). Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells (2). IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles (3). |
Research Area | Immune System antibody; Signaling Transduction antibody |
Calculated MW | 20 kDa |