ARG54647

anti-IL22 antibody

anti-IL22 antibody for ELISA,ICC/IF,Western blot and Human,Mouse,Rat

Immune System antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes IL22
Tested Reactivity Hu, Ms, Rat
Tested Application ELISA, ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name IL22
Antigen Species Human
Immunogen Synthetic peptide (17 aa) within aa. 90-140 of Human IL-22 protein.
Conjugation Un-conjugated
Alternate Names Interleukin-22; zcyto18; IL-TIF; IL-22; IL-21; IL-D110; TIFa; ILTIF; TIFIL-23; IL-10-related T-cell-derived-inducible factor; Cytokine Zcyto18

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
ICC/IF5 - 20 μg/ml
WB1 - 2 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa Cell Lysate

Properties

Form Liquid
Purification Immunogen affinity purified
Buffer PBS and 0.02% Sodium azide.
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 50616 Human IL22

GeneID: 50929 Mouse IL22

Swiss-port # Q9GZX6 Human Interleukin-22

Swiss-port # Q9JJY9 Mouse Interleukin-22

Gene Symbol IL22
Gene Full Name interleukin 22
Background Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation (1). Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells (2). IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles (3).
Research Area Immune System antibody; Signaling Transduction antibody
Calculated MW 20 kDa