ARG21470
anti-IL5 antibody [TRFK4] (Biotin)
anti-IL5 antibody [TRFK4] (Biotin) for ELISA,ELISPOT,ICC/IF,IHC-Frozen sections,Neutralizing,Purification and Mouse
Overview
Product Description | Biotin-conjugated Rat Monoclonal antibody [TRFK4 ] recognizes IL5 |
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Tested Reactivity | Ms |
Tested Application | ELISA, ELISPOT, ICC/IF, IHC-Fr, Neut, Puri |
Specificity | Mouse IL-5. |
Host | Rat |
Clonality | Monoclonal |
Clone | TRFK4 |
Isotype | IgG2a, kappa |
Target Name | IL5 |
Antigen Species | Mouse |
Immunogen | Semi-purified T cell clone supernatant |
Conjugation | Biotin |
Alternate Names | Eosinophil differentiation factor; EDF; IL-5; TRF; T-cell replacing factor; B-cell differentiation factor I; Interleukin-5 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Buffer | PBS and 0.1% Sodium azide. |
Preservative | 0.1% Sodium azide |
Concentration | 0.5 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | IL5 |
Gene Full Name | interleukin 5 |
Background | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013] |
Function | Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. [UniProt] |
Calculated MW | 15 kDa |